Sappanone A alleviates hypoxia/reoxygenation-induced cardiomyocytes injury through inhibition of mitochondrial apoptosis and activation of PI3K–Akt–Gsk-3β pathway

Myocardial ischemia reperfusion injury (MIRI) is a complex pathophysiological process involved with the activation of oxidative stress, inflammation and apoptosis. Sappanone A (SA), a homoisoflavanone isolated from the heartwood of Caesalpinia sappan L., could exhibit antioxidant, anti-inflammatory...

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Detalles Bibliográficos
Autores principales: Shi, Xiaojing, Tao, Guizhou, Ji, Lili, Tian, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cardiovascular System & Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042124/
https://www.ncbi.nlm.nih.gov/pubmed/32095825
http://dx.doi.org/10.1042/BSR20192442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042124/
https://www.ncbi.nlm.nih.gov/pubmed/32095825
http://dx.doi.org/10.1042/BSR20192442

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