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Investigation of sirtuin 1 polymorphisms in relation to the risk of colorectal cancer by molecular subtype
Sirtuin 1 (SIRT1), a histone deacetylase, is involved in maintenance of genetic stability, inflammation, immune response, metabolism (energy-sensing molecule) and colorectal tumorigenesis. We investigated SIRT1’s specific role in colorectal tumorigenesis by studying SIRT1 polymorphisms in relation t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042277/ https://www.ncbi.nlm.nih.gov/pubmed/32098999 http://dx.doi.org/10.1038/s41598-020-60300-2 |