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Virtual screening as a tool to discover new β-haematin inhibitors with activity against malaria parasites
Malaria remains a major public health problem. With the loss of antimalarials to resistance, the malaria burden will likely continue for decades. New antimalarial scaffolds are crucial to avoid cross-resistance. Here, we present the first structure based virtual screening using the β-haematin crysta...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042288/ https://www.ncbi.nlm.nih.gov/pubmed/32099045 http://dx.doi.org/10.1038/s41598-020-60221-0 |