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Virtual screening as a tool to discover new β-haematin inhibitors with activity against malaria parasites

Malaria remains a major public health problem. With the loss of antimalarials to resistance, the malaria burden will likely continue for decades. New antimalarial scaffolds are crucial to avoid cross-resistance. Here, we present the first structure based virtual screening using the β-haematin crysta...

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Detalles Bibliográficos
Autores principales:	de Sousa, Ana Carolina C., Combrinck, Jill M., Maepa, Keletso, Egan, Timothy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042288/ https://www.ncbi.nlm.nih.gov/pubmed/32099045 http://dx.doi.org/10.1038/s41598-020-60221-0

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