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AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

The AMP-activated protein kinase (AMPK) is a master sensor of the cellular energy status that is crucial for the adaptive response to limited energy availability. AMPK is implicated in the regulation of many cellular processes, including autophagy. However, the precise mechanisms by which AMPK contr...

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Detalles Bibliográficos
Autores principales: Dohmen, Marc, Krieg, Sarah, Agalaridis, Georgios, Zhu, Xiaoqing, Shehata, Saifeldin N., Pfeiffenberger, Elisabeth, Amelang, Jan, Bütepage, Mareike, Buerova, Elena, Pfaff, Carolina M., Chanda, Dipanjan, Geley, Stephan, Preisinger, Christian, Sakamoto, Kei, Lüscher, Bernhard, Neumann, Dietbert, Vervoorts, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042329/
https://www.ncbi.nlm.nih.gov/pubmed/32098961
http://dx.doi.org/10.1038/s41467-020-14812-0