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Preferential HLA-B27 Allorecognition Displayed by Multiple Cross-Reactive Antiviral CD8(+) T Cell Receptors

T cells provide essential immunosurveillance to combat and eliminate infection from pathogens, yet these cells can also induce unwanted immune responses via T cell receptor (TCR) cross-reactivity, also known as heterologous immunity. Indeed, pathogen-induced TCR cross-reactivity has shown to be a co...

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Detalles Bibliográficos
Autores principales: Rowntree, Louise C., van den Heuvel, Heleen, Sun, Jessica, D'Orsogna, Lloyd J., Nguyen, Thi H. O., Claas, Frans H. J., Rossjohn, Jamie, Kotsimbos, Tom C., Purcell, Anthony W., Mifsud, Nicole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042382/
https://www.ncbi.nlm.nih.gov/pubmed/32140156
http://dx.doi.org/10.3389/fimmu.2020.00248