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DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection

OBJECTIVES: The host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-6A, HHV-6B or HHV-7 is able to modify DNA s...

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Detalles Bibliográficos
Autores principales: Bortolotti, Daria, Gentili, Valentina, Caselli, Elisabetta, Sicolo, Mariangela, Soffritti, Irene, D’Accolti, Maria, Barao, Isabel, Rotola, Antonella, Di Luca, Dario, Rizzo, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042408/
https://www.ncbi.nlm.nih.gov/pubmed/32140147
http://dx.doi.org/10.3389/fmicb.2020.00226