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Orthologous promoters from related methylotrophic yeasts surpass expression of endogenous promoters of Pichia pastoris
Methylotrophic yeasts such as Komagataella phaffii (syn. Pichia pastoris, Pp), Hansenula polymorpha (Hp), Candida boidinii (Cb) and Pichia methanolica (Pm) are widely used protein production platforms. Typically, strong, tightly regulated promoters of genes coding for their methanol utilization (MUT...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042429/ https://www.ncbi.nlm.nih.gov/pubmed/32100120 http://dx.doi.org/10.1186/s13568-020-00972-1 |