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Percutaneous absorption and brain distribution facilitation of borneol on tetramethylpyrazine in a microemulsion-based transdermal therapeutic system

In this study, we show that the percutaneous absorption and brain distribution of tetramethylpyrazine (TMP) is enhanced when combined with borneol (BN) in a microemulsion-based transdermal therapeutic system (ME-TTS). The formulation of the TMP and BN microemulsion (TEM-BN-ME) was optimized in skin...

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Detalles Bibliográficos
Autores principales: Hu, Xiaoge, Cheng, Ning, Zhao, Jihui, Piao, Xianghua, Yan, Yulu, Zhang, Qibo, Zhou, Kuan, Zhang, Yongtai, Feng, Nianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042483/
https://www.ncbi.nlm.nih.gov/pubmed/32104460
http://dx.doi.org/10.1016/j.ajps.2018.06.003