Evaluation of the Role of Human DNAJAs in the Response to Cytotoxic Chemotherapeutic Agents in a Yeast Model System

Heat-shock proteins (HSPs) play a crucial role in maintaining protein stability for cell survival during stress-induced insults. Overexpression of HSPs in cancer cells results in antiapoptotic activity contributing to cancer cell survival and restricting the efficacy of cytotoxic chemotherapy, which...

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Detalles Bibliográficos
Autores principales: Whitmore, Aurellia, Freeny, Devon, Sojourner, Samantha J., Miles, Jana S., Graham, Willie M., Flores-Rozas, Hernan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042521/
https://www.ncbi.nlm.nih.gov/pubmed/32149145
http://dx.doi.org/10.1155/2020/9097638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042521/
https://www.ncbi.nlm.nih.gov/pubmed/32149145
http://dx.doi.org/10.1155/2020/9097638

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