Cargando…
Evaluation of the Role of Human DNAJAs in the Response to Cytotoxic Chemotherapeutic Agents in a Yeast Model System
Heat-shock proteins (HSPs) play a crucial role in maintaining protein stability for cell survival during stress-induced insults. Overexpression of HSPs in cancer cells results in antiapoptotic activity contributing to cancer cell survival and restricting the efficacy of cytotoxic chemotherapy, which...
Autores principales: | Whitmore, Aurellia, Freeny, Devon, Sojourner, Samantha J., Miles, Jana S., Graham, Willie M., Flores-Rozas, Hernan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042521/ https://www.ncbi.nlm.nih.gov/pubmed/32149145 http://dx.doi.org/10.1155/2020/9097638 |
Ejemplares similares
-
Synergistic Effect of Endogenous and Exogenous Aldehydes on Doxorubicin Toxicity in Yeast
por: Miles, Jana S., et al.
Publicado: (2018) -
Inactivation of chromatin remodeling factors sensitizes cells to selective cytotoxic stress
por: Freeman, Miles D, et al.
Publicado: (2014) -
Evaluation of Chemotherapeutic Agents
por: Engstrom, W. W.
Publicado: (1949) -
Human Hsp40 proteins, DNAJA1 and DNAJA2, as potential targets of the immune response triggered by bacterial DnaJ in rheumatoid arthritis
por: Kotlarz, Agnieszka, et al.
Publicado: (2013) -
DNAJA4 Promotes the Replication of the Chinese Giant Salamander Iridovirus
por: Liu, Zijing, et al.
Publicado: (2022)