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Defects of CTLA-4 Are Associated with Regulatory T Cells in Myasthenia Gravis Implicated by Intravenous Immunoglobulin Therapy

Myasthenia gravis (MG) is a CD4(+) T cell-dependent autoimmune disease resulting from aberrant immune response mediated by circulating autoantibodies at the neuromuscular junction. Intravenous immunoglobulin (IVIg) is an expensive and commonly used immunotherapeutic approach to treat patients with M...

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Detalles Bibliográficos
Autores principales: Xu, Wenhua, Ren, Mingshan, Ghosh, Swagata, Qian, Kai, Luo, Zhaofeng, Zhang, Aimei, Zhang, Cuiping, Cui, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042523/
https://www.ncbi.nlm.nih.gov/pubmed/32148437
http://dx.doi.org/10.1155/2020/3645157