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Autophagy Inhibition Potentiates the Anticancer Effects of a Bendamustine Derivative NL-101 in Acute T Lymphocytic Leukemia

Acute T lymphocytic leukemia (T-ALL) is an aggressive hematologic resulting from the malignant transformation of T-cell progenitors. Drug resistance and relapse are major difficulties in the treatment of T-ALL. Here, we report the antitumor potency of NL-101, a compound that combines the nitrogen mu...

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Detalles Bibliográficos
Autores principales: Gao, Hang, Lou, Siyue, Hong, Huanwu, Ge, Qiufu, Zhao, Huajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042524/
https://www.ncbi.nlm.nih.gov/pubmed/32149078
http://dx.doi.org/10.1155/2020/1520651