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Role of Plasmodium falciparum Kelch 13 Protein Mutations in P. falciparum Populations from Northeastern Myanmar in Mediating Artemisinin Resistance

Mutations in the Plasmodium falciparum Kelch 13 (PfK13) protein are associated with artemisinin resistance. PfK13 is essential for asexual erythrocytic development, but its function is not known. We tagged the PfK13 protein with green fluorescent protein in P. falciparum to study its expression and...

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Detalles Bibliográficos
Autores principales: Siddiqui, Faiza Amber, Boonhok, Rachasak, Cabrera, Mynthia, Mbenda, Huguette Gaelle Ngassa, Wang, Meilian, Min, Hui, Liang, Xiaoying, Qin, Junling, Zhu, Xiaotong, Miao, Jun, Cao, Yaming, Cui, Liwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042691/
https://www.ncbi.nlm.nih.gov/pubmed/32098812
http://dx.doi.org/10.1128/mBio.01134-19