The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation

The efficacy of current antimalarial drugs is threatened by reduced susceptibility of Plasmodium falciparum to artemisinin, associated with mutations in pfkelch13. Another gene with variants known to modulate the response to artemisinin encodes the μ subunit of the AP-2 adaptin trafficking complex....

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Detalles Bibliográficos
Autores principales: Henrici, Ryan C., Edwards, Rachel L., Zoltner, Martin, van Schalkwyk, Donelly A., Hart, Melissa N., Mohring, Franziska, Moon, Robert W., Nofal, Stephanie D., Patel, Avnish, Flueck, Christian, Baker, David A., Odom John, Audrey R., Field, Mark C., Sutherland, Colin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042695/
https://www.ncbi.nlm.nih.gov/pubmed/32098816
http://dx.doi.org/10.1128/mBio.02918-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042695/
https://www.ncbi.nlm.nih.gov/pubmed/32098816
http://dx.doi.org/10.1128/mBio.02918-19

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