Cargando…
Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
Broadly neutralizing antibodies (bNAbs) represent a promising approach to prevent and treat HIV-1 infection. However, viral escape through mutation of the HIV-1 envelope glycoprotein (Env) limits clinical applications. Here we describe 1-18, a new V(H)1-46-encoded CD4 binding site (CD4bs) bNAb with...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042716/ https://www.ncbi.nlm.nih.gov/pubmed/32004464 http://dx.doi.org/10.1016/j.cell.2020.01.010 |