Cargando…

Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease

IMPORTANCE: Monogenic familial hypercholesterolemia (FH) is associated with lifelong elevations in low-density lipoprotein cholesterol (LDL-C) levels and increased risk of atherosclerotic cardiovascular disease (CVD). However, many individuals with hypercholesterolemia have a polygenic rather than a...

Descripción completa

Detalles Bibliográficos
Autores principales: Trinder, Mark, Francis, Gordon A., Brunham, Liam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042820/
https://www.ncbi.nlm.nih.gov/pubmed/32049305
http://dx.doi.org/10.1001/jamacardio.2019.5954