Postzygotic mosaicism in cerebral cavernous malformation

BACKGROUND: Cerebral cavernous malformations (CCMs) can cause severe neurological morbidity but our understanding of the mechanisms that drive CCM formation and growth is still incomplete. Recent experimental data suggest that dysfunctional CCM3-deficient endothelial cell clones form cavernous lesio...

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Detalles Bibliográficos
Autores principales: Rath, Matthias, Pagenstecher, Axel, Hoischen, Alexander, Felbor, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Somatic Mosaicism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042965/
https://www.ncbi.nlm.nih.gov/pubmed/31446422
http://dx.doi.org/10.1136/jmedgenet-2019-106182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042965/
https://www.ncbi.nlm.nih.gov/pubmed/31446422
http://dx.doi.org/10.1136/jmedgenet-2019-106182

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