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Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

The transcriptional corepressor complex CoREST is one of seven histone deacetylase complexes that regulate the genome through controlling chromatin acetylation. The CoREST complex is unique in containing both histone demethylase and deacetylase enzymes, LSD1 and HDAC1, held together by the RCOR1 sca...

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Detalles Bibliográficos
Autores principales: Song, Yun, Dagil, Lisbeth, Fairall, Louise, Robertson, Naomi, Wu, Mingxuan, Ragan, T.J., Savva, Christos G., Saleh, Almutasem, Morone, Nobuhiro, Kunze, Micha B.A., Jamieson, Andrew G., Cole, Philip A., Hansen, D. Flemming, Schwabe, John W.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043024/
https://www.ncbi.nlm.nih.gov/pubmed/32101746
http://dx.doi.org/10.1016/j.celrep.2020.01.091