Ca(2+) mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione

BACKGROUND: The lumen of the endoplasmic reticulum (ER) acts as a cellular Ca(2+) store and a site for oxidative protein folding, which is controlled by the reduced glutathione (GSH) and glutathione-disulfide (GSSG) redox pair. Although depletion of luminal Ca(2+) from the ER provokes a rapid and re...

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Detalles Bibliográficos
Autores principales: Lizák, Beáta, Birk, Julia, Zana, Melinda, Kosztyi, Gergely, Kratschmar, Denise V., Odermatt, Alex, Zimmermann, Richard, Geiszt, Miklós, Appenzeller-Herzog, Christian, Bánhegyi, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043043/
https://www.ncbi.nlm.nih.gov/pubmed/32101139
http://dx.doi.org/10.1186/s12915-020-0749-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043043/
https://www.ncbi.nlm.nih.gov/pubmed/32101139
http://dx.doi.org/10.1186/s12915-020-0749-y

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