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Lens Stretching Modulates Lens Epithelial Cell Proliferation via YAP Regulation

PURPOSE: The continuous growth of the lens throughout life may contribute to the onset of age-related conditions in the lens (i.e., presbyopia and cataract). Volumetric growth is the result of continuous proliferation of lens epithelial cells (LECs). The driving factors controlling LEC proliferation...

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Detalles Bibliográficos
Autores principales: Kumar, Bharat, Chandler, Heather L., Plageman, Timothy, Reilly, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043215/
https://www.ncbi.nlm.nih.gov/pubmed/31546253
http://dx.doi.org/10.1167/iovs.19-26893