Cargando…

Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold

The scavenger receptor cysteine-rich (SRCR) family of proteins comprises more than 20 membrane-associated and secreted molecules. Characterised by the presence of one or more copies of the ∼110 amino-acid SRCR domain, this class of proteins have widespread functions as antimicrobial molecules, scave...

Descripción completa

Detalles Bibliográficos
Autores principales: Reichhardt, Martin P, Loimaranta, Vuokko, Lea, Susan M, Johnson, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043408/
https://www.ncbi.nlm.nih.gov/pubmed/32098784
http://dx.doi.org/10.26508/lsa.201900502