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A method for gene knockdown in the retina using a lipid-based carrier

PURPOSE: The use of small non-coding nucleic acids, such as siRNA and miRNA, has allowed for a deeper understanding of gene functions, as well as for development of gene therapies for complex neurodegenerative diseases, including retinal degeneration. For effective delivery into the eye and transfec...

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Detalles Bibliográficos
Autores principales: Chu-Tan, Joshua A., Fernando, Nilisha, Aggio-Bruce, Riemke, Cioanca, Adrian V., Valter, Krisztina, Andronikou, Nektaria, deMollerat du Jeu, Xavier, Rutar, Matt, Provis, Jan, Natoli, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043644/
https://www.ncbi.nlm.nih.gov/pubmed/32165826