Cargando…
A method for gene knockdown in the retina using a lipid-based carrier
PURPOSE: The use of small non-coding nucleic acids, such as siRNA and miRNA, has allowed for a deeper understanding of gene functions, as well as for development of gene therapies for complex neurodegenerative diseases, including retinal degeneration. For effective delivery into the eye and transfec...
Autores principales: | Chu-Tan, Joshua A., Fernando, Nilisha, Aggio-Bruce, Riemke, Cioanca, Adrian V., Valter, Krisztina, Andronikou, Nektaria, deMollerat du Jeu, Xavier, Rutar, Matt, Provis, Jan, Natoli, Riccardo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043644/ https://www.ncbi.nlm.nih.gov/pubmed/32165826 |
Ejemplares similares
-
The broad-spectrum chemokine inhibitor NR58-3.14.3 modulates macrophage-mediated inflammation in the diseased retina
por: Fernando, Nilisha, et al.
Publicado: (2016) -
Subretinal macrophages produce classical complement activator C1q leading to the progression of focal retinal degeneration
por: Jiao, Haihan, et al.
Publicado: (2018) -
Synthesis and Propagation of Complement C3 by Microglia/Monocytes in the Aging Retina
por: Rutar, Matt, et al.
Publicado: (2014) -
Functional microRNA targetome undergoes degeneration-induced shift in the retina
por: Chu-Tan, Joshua A., et al.
Publicado: (2021) -
Chemokine-mediated inflammation in the degenerating retina is coordinated by Müller cells, activated microglia, and retinal pigment epithelium
por: Rutar, Matt, et al.
Publicado: (2015)