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Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions
Temozolomide (TMZ) is a drug of choice in glioblastoma treatment. Its therapeutic applications expand also beyond high grade gliomas. However, a significant number of recurrences and resistance to the drug is observed. The key factor in each chemotherapy is to achieve the therapeutic doses of a drug...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043761/ https://www.ncbi.nlm.nih.gov/pubmed/32101575 http://dx.doi.org/10.1371/journal.pone.0229534 |