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Ameliorative effects of silymarin on HCl-induced acute lung injury in rats; role of the Nrf-2/HO-1 pathway

OBJECTIVE(S): Aspiration is a common cause of acute lung injury (ALI), which lacks an effective treatment. Inflammation and oxidative stress play key roles in ALI development. Silymarin is an active extract of Silybum marianum plant seeds (milk thistle). Silymarin has potent anti-inflammatory and an...

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Detalles Bibliográficos
Autores principales: Ahmed, Rasha F, Moussa, Rabab A, Eldemerdash, Reda S, Zakaria, Mahmoud M, Abdel-Gaber, Seham A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043873/
https://www.ncbi.nlm.nih.gov/pubmed/32133068
http://dx.doi.org/10.22038/IJBMS.2019.14069