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Immunization against Leishmania major infection in BALB/c mice using a subunit-based DNA vaccine derived from TSA, LmSTI1, KMP11, and LACK predominant antigens

OBJECTIVE(S): To design a multivalent DNA vaccine encoding the most immunogenic regions of the Leishmania major antigens including TSA (Thiol-specific antioxidant protein), LmSTI1 (Leishmania major stress-inducible protein1), LACK (Leishmania homologue of receptors for activated C Kinase), and KMP11...

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Detalles Bibliográficos
Autores principales: Salehi-Sangani, Ghodratollah, Mohebali, Mehdi, Jajarmi, Vahid, Khamesipour, Ali, Bandehpour, Mojgan, Mahmoudi, Mahmoud, Zahedi-Zavaram, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043880/
https://www.ncbi.nlm.nih.gov/pubmed/32133069
http://dx.doi.org/10.22038/IJBMS.2019.14051