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Exploring the role of dimethylarginine dimethylaminohydrolase-mediated reduction in tissue asymmetrical dimethylarginine levels in cardio-protective mechanism of ischaemic postconditioning in rats

OBJECTIVE(S): Reperfusion of ischaemic myocardium results in reduced nitric oxide (NO) biosynthesis by endothelial nitric oxide synthase (eNOS) leading to endothelial dysfunction and subsequent tissue damage. Impaired NO biosynthesis may be partly due to increased levels of asymmetrical dimethylargi...

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Detalles Bibliográficos
Autores principales: Kaur, Kamaldeep, Singh, Nirmal, Dhawan, R. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043882/
https://www.ncbi.nlm.nih.gov/pubmed/32133059
http://dx.doi.org/10.22038/IJBMS.2019.14067