Nitric oxide disrupts bacterial cytokinesis by poisoning purine metabolism

Cytostasis is the most salient manifestation of the potent antimicrobial activity of nitric oxide (NO), yet the mechanism by which NO disrupts bacterial cell division is unknown. Here, we show that in respiring Escherichia coli, Salmonella, and Bacillus subtilis, NO arrests the first step in divisio...

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Detalles Bibliográficos
Autores principales: Jones-Carson, Jessica, Yahashiri, Atsushi, Kim, Ju-Sim, Liu, Lin, Fitzsimmons, Liam F., Weiss, David S., Vázquez-Torres, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043908/
https://www.ncbi.nlm.nih.gov/pubmed/32133408
http://dx.doi.org/10.1126/sciadv.aaz0260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043908/
https://www.ncbi.nlm.nih.gov/pubmed/32133408
http://dx.doi.org/10.1126/sciadv.aaz0260

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