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Nitric oxide disrupts bacterial cytokinesis by poisoning purine metabolism
Cytostasis is the most salient manifestation of the potent antimicrobial activity of nitric oxide (NO), yet the mechanism by which NO disrupts bacterial cell division is unknown. Here, we show that in respiring Escherichia coli, Salmonella, and Bacillus subtilis, NO arrests the first step in divisio...
Autores principales: | Jones-Carson, Jessica, Yahashiri, Atsushi, Kim, Ju-Sim, Liu, Lin, Fitzsimmons, Liam F., Weiss, David S., Vázquez-Torres, Andrés |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043908/ https://www.ncbi.nlm.nih.gov/pubmed/32133408 http://dx.doi.org/10.1126/sciadv.aaz0260 |
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