CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

Depleting regulatory T cells (T(reg) cells) to counteract immunosuppressive features of the tumor microenvironment (TME) is an attractive strategy for cancer treatment; however, autoimmunity due to systemic impairment of their suppressive function limits its therapeutic potential. Elucidating approa...

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Detalles Bibliográficos
Autores principales: Wang, Haiping, Franco, Fabien, Tsui, Yao-Chen, Xie, Xin, Trefny, Marcel P., Zappasodi, Roberta, Mohmood, Syed Raza, Fernández-García, Juan, Tsai, Chin-Hsien, Schulze, Isabell, Picard, Florence, Meylan, Etienne, Silverstein, Roy, Goldberg, Ira, Fendt, Sarah-Maria, Wolchok, Jedd D., Merghoub, Taha, Jandus, Camilla, Zippelius, Alfred, Ho, Ping-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043937/
https://www.ncbi.nlm.nih.gov/pubmed/32066953
http://dx.doi.org/10.1038/s41590-019-0589-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043937/
https://www.ncbi.nlm.nih.gov/pubmed/32066953
http://dx.doi.org/10.1038/s41590-019-0589-5

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