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Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4(+) T cells

Differentiation of CD4(+) T cells into either follicular helper T (T(FH)) or type 1 helper T (T(H)1) cells influences the balance between humoral and cellular adaptive immunity, but the mechanisms whereby pathogens elicit distinct effector cells are incompletely understood. Here, we analyzed the spa...

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Detalles Bibliográficos
Autores principales: De Giovanni, Marco, Cutillo, Valeria, Giladi, Amir, Sala, Eleonora, Maganuco, Carmela G., Medaglia, Chiara, Di Lucia, Pietro, Bono, Elisa, Cristofani, Claudia, Consolo, Eleonora, Giustini, Leonardo, Fiore, Alessandra, Eickhoff, Sarah, Kastenmüller, Wolfgang, Amit, Ido, Kuka, Mirela, Iannacone, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043938/
https://www.ncbi.nlm.nih.gov/pubmed/32066949
http://dx.doi.org/10.1038/s41590-020-0596-6