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Lung CD4(+) resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia
Previous pneumococcal experience establishes lung-resident IL-17A-producing CD4(+) memory T(RM) cells that accelerate neutrophil recruitment against heterotypic pneumococci. Herein, we unravel a novel crosstalk between CD4(+) T(RM) cells and lung epithelial cells underlying this protective immunity....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044037/ https://www.ncbi.nlm.nih.gov/pubmed/31748706 http://dx.doi.org/10.1038/s41385-019-0229-2 |