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Lung CD4(+) resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia

Previous pneumococcal experience establishes lung-resident IL-17A-producing CD4(+) memory T(RM) cells that accelerate neutrophil recruitment against heterotypic pneumococci. Herein, we unravel a novel crosstalk between CD4(+) T(RM) cells and lung epithelial cells underlying this protective immunity....

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Detalles Bibliográficos
Autores principales: Shenoy, Anukul T., Wasserman, Gregory A., Arafa, Emad I., Wooten, Alicia K., Smith, Nicole M.S., Martin, Ian M.C., Jones, Matthew R., Quinton, Lee J., Mizgerd, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044037/
https://www.ncbi.nlm.nih.gov/pubmed/31748706
http://dx.doi.org/10.1038/s41385-019-0229-2