Cargando…
Lung CD4(+) resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia
Previous pneumococcal experience establishes lung-resident IL-17A-producing CD4(+) memory T(RM) cells that accelerate neutrophil recruitment against heterotypic pneumococci. Herein, we unravel a novel crosstalk between CD4(+) T(RM) cells and lung epithelial cells underlying this protective immunity....
Autores principales: | Shenoy, Anukul T., Wasserman, Gregory A., Arafa, Emad I., Wooten, Alicia K., Smith, Nicole M.S., Martin, Ian M.C., Jones, Matthew R., Quinton, Lee J., Mizgerd, Joseph P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044037/ https://www.ncbi.nlm.nih.gov/pubmed/31748706 http://dx.doi.org/10.1038/s41385-019-0229-2 |
Ejemplares similares
-
Unique Roles for Streptococcus pneumoniae Phosphodiesterase 2 in Cyclic di-AMP Catabolism and Macrophage Responses
por: Wooten, Alicia K., et al.
Publicado: (2020) -
Recruitment and training of alveolar macrophages after pneumococcal pneumonia
por: Arafa, Emad I., et al.
Publicado: (2022) -
Seedy CD8+ T(RM) cells in aging lungs drive susceptibility to pneumonia and sequelae
por: Shenoy, Anukul T., et al.
Publicado: (2021) -
Regionally Compartmentalized Resident Memory T Cells Mediate Naturally Acquired Protection Against Pneumococcal Pneumonia
por: Smith, N.M.S., et al.
Publicado: (2017) -
Lectin-like oxidized low-density lipoprotein receptor 1 attenuates pneumonia-induced lung injury
por: Korkmaz, Filiz T., et al.
Publicado: (2022)