Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8(+) T cells

Tissue-resident memory T cells (T(RM) cells) are critical for cellular immunity to respiratory pathogens and reside in both the airways and the interstitium. In the present study, we found that the airway environment drove transcriptional and epigenetic changes that specifically regulated the cytoly...

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Detalles Bibliográficos
Autores principales: Hayward, Sarah L., Scharer, Christopher D., Cartwright, Emily K., Takamura, Shiki, Li, Zheng-Rong Tiger, Boss, Jeremy M., Kohlmeier, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044042/
https://www.ncbi.nlm.nih.gov/pubmed/31953534
http://dx.doi.org/10.1038/s41590-019-0584-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044042/
https://www.ncbi.nlm.nih.gov/pubmed/31953534
http://dx.doi.org/10.1038/s41590-019-0584-x

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