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Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8(+) T cells
Tissue-resident memory T cells (T(RM) cells) are critical for cellular immunity to respiratory pathogens and reside in both the airways and the interstitium. In the present study, we found that the airway environment drove transcriptional and epigenetic changes that specifically regulated the cytoly...
Autores principales: | Hayward, Sarah L., Scharer, Christopher D., Cartwright, Emily K., Takamura, Shiki, Li, Zheng-Rong Tiger, Boss, Jeremy M., Kohlmeier, Jacob E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044042/ https://www.ncbi.nlm.nih.gov/pubmed/31953534 http://dx.doi.org/10.1038/s41590-019-0584-x |
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