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Treg-expression of CIS suppresses allergic airway inflammation through antagonizing an autonomous TH2 program

Maintenance of regulatory T (Treg) cells is crucial for the regulatory function of Treg cells in immune homeostasis and self-tolerance; however, the detailed underlying mechanisms remain elusive. In the current study, we found that the cytokine suppressor CIS is required for maintenance of Treg cell...

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Detalles Bibliográficos
Autores principales: Zheng, Handong, Wu, Xiang, Wu, Dandan, Jiang, Ruo-Lan, Castillo, Eliseo F., Chock, Cameron J., Zhou, Qin, Liu, Meilian, Dong, Chen, Yang, Xuexian O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044046/
https://www.ncbi.nlm.nih.gov/pubmed/31780776
http://dx.doi.org/10.1038/s41385-019-0236-3