Type I IFN ineffectively activates neonatal dendritic cells limiting respiratory antiviral T cell responses

Insufficient T cell responses contribute to the increased burden of viral respiratory disease in infancy. Neonatal dendritic cells (DCs) often provide defective activation of pathogen-specific T cells through mechanisms that are incompletely understood, which hinders vaccine design for this vulnerab...

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Detalles Bibliográficos
Autores principales: Lau-Kilby, Annie W., Turfkruyer, Mathilde, Kehl, Margaret, Yang, Lijuan, Buchholz, Ursula J., Hickey, Kimberly, Malloy, Allison M.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044048/
https://www.ncbi.nlm.nih.gov/pubmed/31797910
http://dx.doi.org/10.1038/s41385-019-0234-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044048/
https://www.ncbi.nlm.nih.gov/pubmed/31797910
http://dx.doi.org/10.1038/s41385-019-0234-5

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