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Type I IFN ineffectively activates neonatal dendritic cells limiting respiratory antiviral T cell responses
Insufficient T cell responses contribute to the increased burden of viral respiratory disease in infancy. Neonatal dendritic cells (DCs) often provide defective activation of pathogen-specific T cells through mechanisms that are incompletely understood, which hinders vaccine design for this vulnerab...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044048/ https://www.ncbi.nlm.nih.gov/pubmed/31797910 http://dx.doi.org/10.1038/s41385-019-0234-5 |