HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells

HIV-1 infection is associated with heightened inflammation and excess risk of cardiovascular disease, cancer, and other complications. These pathologies persist despite antiretroviral therapy (ART). In two independent cohorts, we found that innate lymphoid cells (ILCs) were depleted in the blood and...

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Detalles Bibliográficos
Autores principales: Wang, Yetao, Lifshitz, Lawrence, Gellatly, Kyle, Vinton, Carol L., Busman-Sahay, Kathleen, McCauley, Sean, Vangala, Pranitha, Kim, Kyusik, Derr, Alan, Jaiswal, Smita, Kucukural, Alper, McDonel, Patrick, Hunt, Peter W., Greenough, Thomas, Houghton, JeanMarie, Somsouk, Ma, Estes, Jacob D., Brenchley, Jason M., Garber, Manuel, Deeks, Steven G., Luban, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044076/
https://www.ncbi.nlm.nih.gov/pubmed/32066947
http://dx.doi.org/10.1038/s41590-020-0593-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044076/
https://www.ncbi.nlm.nih.gov/pubmed/32066947
http://dx.doi.org/10.1038/s41590-020-0593-9

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