Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer

OBJECTIVE: High rates of systemic failure in locally advanced rectal cancer call for a rational use of conventional therapies to foster tumor-defeating immunity. METHODS: We analyzed the high-mobility group box-1 (HMGB1) protein, a measure of immunogenic cell death (ICD), in plasma sampled from 50 p...

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Detalles Bibliográficos
Autores principales: Bains, Simer J., Abrahamsson, Hanna, Flatmark, Kjersti, Dueland, Svein, Hole, Knut H., Seierstad, Therese, Redalen, Kathrine Røe, Meltzer, Sebastian, Ree, Anne Hansen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044156/
https://www.ncbi.nlm.nih.gov/pubmed/31893287
http://dx.doi.org/10.1007/s00262-019-02458-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044156/
https://www.ncbi.nlm.nih.gov/pubmed/31893287
http://dx.doi.org/10.1007/s00262-019-02458-x

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