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Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near complete return of chloroquine susceptible falciparum malaria in Southeast of Tanzania

In Tanzania, chloroquine was replaced by sulphadoxine- pyrimethamine (SP) as a first-line for treatment of uncomplicated malaria. Due to high resistance in malaria parasites, SP lasted for only 5 years and by the end of 2006 it was replaced with the current artemisinin combination therapy. We theref...

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Detalles Bibliográficos
Autores principales: Bwire, George M., Ngasala, Billy, Mikomangwa, Wigilya P., Kilonzi, Manase, Kamuhabwa, Appolinary A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044163/
https://www.ncbi.nlm.nih.gov/pubmed/32103124
http://dx.doi.org/10.1038/s41598-020-60549-7