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Mechanotransduction Activity Facilitates Hair Cell Toxicity Caused by the Heavy Metal Cadmium

Hair cells are sensitive to many insults including environmental toxins such as heavy metals. We show here that cadmium can consistently kill hair cells of the zebrafish lateral line. Disrupting hair cell mechanotransduction genetically or pharmacologically significantly reduces the amount of hair c...

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Detalles Bibliográficos
Autores principales: Schmid, Caleigh, Alampi, Isabella, Briggs, Jay, Tarcza, Kelly, Stawicki, Tamara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044240/
https://www.ncbi.nlm.nih.gov/pubmed/32153368
http://dx.doi.org/10.3389/fncel.2020.00037