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Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy

Lactate dehydrogenase C (LDHC) is an archetypical cancer testis antigen with limited expression in adult tissues and re-expression in tumors. This restricted expression pattern together with the important role of LDHC in cancer metabolism renders LDHC a potential target for immunotherapy. This study...

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Detalles Bibliográficos
Autores principales: Thomas, Remy, Shaath, Hibah, Naik, Adviti, Toor, Salman M., Elkord, Eyad, Decock, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044258/
https://www.ncbi.nlm.nih.gov/pubmed/31932876
http://dx.doi.org/10.1007/s00262-020-02480-4