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Dissecting the Role of the FGF19-FGFR4 Signaling Pathway in Cancer Development and Progression

Fibroblast growth factor (FGF) receptor 4 (FGFR4) belongs to a family of tyrosine kinase receptor. FGFR4 is highly activated in certain types of cancer and its activation is closely associated with its specific ligand, FGF19. Indeed, FGF19-FGFR4 signaling is implicated in many cellular processes inc...

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Detalles Bibliográficos
Autores principales: Liu, Yanan, Cao, Meng, Cai, Yuepiao, Li, Xiaokun, Zhao, Chengguang, Cui, Ri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044267/
https://www.ncbi.nlm.nih.gov/pubmed/32154250
http://dx.doi.org/10.3389/fcell.2020.00095