Cargando…

Dissecting the Role of the FGF19-FGFR4 Signaling Pathway in Cancer Development and Progression

Fibroblast growth factor (FGF) receptor 4 (FGFR4) belongs to a family of tyrosine kinase receptor. FGFR4 is highly activated in certain types of cancer and its activation is closely associated with its specific ligand, FGF19. Indeed, FGF19-FGFR4 signaling is implicated in many cellular processes inc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yanan, Cao, Meng, Cai, Yuepiao, Li, Xiaokun, Zhao, Chengguang, Cui, Ri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044267/ https://www.ncbi.nlm.nih.gov/pubmed/32154250 http://dx.doi.org/10.3389/fcell.2020.00095

Ejemplares similares

Fgf10/Fgfr2b Signaling in Mammary Gland Development, Homeostasis, and Cancer
por: Rivetti, Stefano, et al.
Publicado: (2020)

FGF Signaling Pathway: A Key Regulator of Stem Cell Pluripotency
por: Mossahebi-Mohammadi, Majid, et al.
Publicado: (2020)

Editorial: Resident and Ectopic FGF Signaling in Development and Disease
por: Wang, Fen, et al.
Publicado: (2020)

Role of FGF10/FGFR2b Signaling in Mouse Digestive Tract Development, Repair and Regeneration Following Injury
por: Lv, Yu-Qing, et al.
Publicado: (2019)

Preferential FGF18/FGFR activity in pseudoglandular versus canalicular stage human lung fibroblasts
por: Belgacemi, Randa, et al.
Publicado: (2023)

An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness
por: Quan, Mei-Yu, et al.
Publicado: (2020)

Fgf10/Fgfr2b Signaling Orchestrates the Symphony of Molecular, Cellular, and Physical Processes Required for Harmonious Airway Branching Morphogenesis
por: Jones, Matthew R., et al.
Publicado: (2021)

Corrigendum: An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness
por: Quan, Mei-Yu, et al.
Publicado: (2020)

Disruption of FGF Signaling Ameliorates Inflammatory Response in Hepatic Stellate Cells
por: Wang, Cong, et al.
Publicado: (2020)

Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling
por: Czaya, Brian, et al.
Publicado: (2022)

Responses of Epibranchial Placodes to Disruptions of the FGF and BMP Signaling Pathways in Embryonic Mice
por: Washausen, Stefan, et al.
Publicado: (2021)

FGF10 and Lipofibroblasts in Lung Homeostasis and Disease: Insights Gained From the Adipocytes
por: Lv, Yu-Qing, et al.
Publicado: (2021)

Investigation of an FGFR-Signaling-Related Prognostic Model and Immune Landscape in Head and Neck Squamous Cell Carcinoma
por: Chen, Qi, et al.
Publicado: (2022)

Roles of FGF Signals in Heart Development, Health, and Disease
por: Itoh, Nobuyuki, et al.
Publicado: (2016)

The Multiple Roles of FGF Signaling in the Developing Spinal Cord
por: Diez del Corral, Ruth, et al.
Publicado: (2017)

FGF signaling in cranial suture development and related diseases
por: Zhao, Xiaolei, et al.
Publicado: (2023)

Isodeoxyelephantopin Inactivates Thioredoxin Reductase 1 and Activates ROS-Mediated JNK Signaling Pathway to Exacerbate Cisplatin Effectiveness in Human Colon Cancer Cells
por: Hong, Lin, et al.
Publicado: (2020)

Regulation of Neurogenesis by FGF Signaling and Neurogenin in the Invertebrate Chordate Ciona
por: Kim, Kwantae, et al.
Publicado: (2020)

The Role of Bmp- and Fgf Signaling Modulating Mouse Proepicardium Cell Fate
por: Garcia-Padilla, Carlos, et al.
Publicado: (2022)

The Multifunctional Contribution of FGF Signaling to Cardiac Development, Homeostasis, Disease and Repair
por: Khosravi, Farhad, et al.
Publicado: (2021)

Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling
por: López-González, Lara, et al.
Publicado: (2021)

Maternal High-Fat Diet Alters the Characteristics of Astrocytes and Worsens the Outcome of Stroke in Rat Offspring, Which Improves After FGF21 Administration
por: Li, Yanxuan, et al.
Publicado: (2022)

Fibroblast Growth Factor 2 Protein Stability Provides Decreased Dependence on Heparin for Induction of FGFR Signaling and Alters ERK Signaling Dynamics
por: Koledova, Zuzana, et al.
Publicado: (2019)

Differential Specificity of Endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in Complex with KLB
por: Yang, Chaofeng, et al.
Publicado: (2012)

Meclozine Attenuates the MARK Pathway in Mammalian Chondrocytes and Ameliorates FGF2-Induced Bone Hyperossification in Larval Zebrafish
por: Takemoto, Genta, et al.
Publicado: (2022)

Increased Expression of Fibulin-1 Is Associated With Hepatocellular Carcinoma Progression by Regulating the Notch Signaling Pathway
por: Gong, Jiao, et al.
Publicado: (2020)

Osteocytes Enhance Osteogenesis by Autophagy-Mediated FGF23 Secretion Under Mechanical Tension
por: Xu, Huiyue, et al.
Publicado: (2022)

Hypoxia Activates Notch4 via ERK/JNK/P38 MAPK Signaling Pathways to Promote Lung Adenocarcinoma Progression and Metastasis
por: Li, Xiaochen, et al.
Publicado: (2021)

Validation of a Novel Fgf10(Cre–ERT2) Knock-in Mouse Line Targeting FGF10(Pos) Cells Postnatally
por: Chu, Xuran, et al.
Publicado: (2021)

Cell Fusion-Related Proteins and Signaling Pathways, and Their Roles in the Development and Progression of Cancer
por: Zhang, Hao, et al.
Publicado: (2022)

Dissection of the microRNA Network Regulating Hedgehog Signaling in Drosophila
por: He, Tao, et al.
Publicado: (2022)

Fgf10 Signaling-Based Evidence for the Existence of an Embryonic Stage Distinct From the Pseudoglandular Stage During Mouse Lung Development
por: Taghizadeh, Sara, et al.
Publicado: (2020)

Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling
por: Huh, Sung-Ho, et al.
Publicado: (2015)

Signaling pathways in hair aging
por: Liang, Aishi, et al.
Publicado: (2023)

3D Cell Culture Models Demonstrate a Role for FGF and WNT Signaling in Regulation of Lung Epithelial Cell Fate and Morphogenesis
por: Rabata, Anas, et al.
Publicado: (2020)

Functional dissection of N-terminal nuclear trafficking signals of SETDB1
por: Eom, Jaemin, et al.
Publicado: (2022)

Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration
por: Wei, Lu, et al.
Publicado: (2019)

Negative Transpulmonary Pressure Disrupts Airway Morphogenesis by Suppressing Fgf10
por: Stanton, Alice E., et al.
Publicado: (2021)

α-Actinin-4 Promotes the Progression of Prostate Cancer Through the Akt/GSK-3β/β-Catenin Signaling Pathway
por: Park, Sungyeon, et al.
Publicado: (2020)

The Diverse Roles of Histone Demethylase KDM4B in Normal and Cancer Development and Progression
por: Wang, Zhongze, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tm185v5osbs7h89m97mus3r8i6