Haloperidol bound D(2) dopamine receptor structure inspired the discovery of subtype selective ligands

The D(2) dopamine receptor (DRD2) is one of the most well-established therapeutic targets for neuropsychiatric and endocrine disorders. Most clinically approved and investigational drugs that target this receptor are known to be subfamily-selective for all three D(2)-like receptors, rather than subt...

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Detalles Bibliográficos
Autores principales: Fan, Luyu, Tan, Liang, Chen, Zhangcheng, Qi, Jianzhong, Nie, Fen, Luo, Zhipu, Cheng, Jianjun, Wang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044277/
https://www.ncbi.nlm.nih.gov/pubmed/32103023
http://dx.doi.org/10.1038/s41467-020-14884-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044277/
https://www.ncbi.nlm.nih.gov/pubmed/32103023
http://dx.doi.org/10.1038/s41467-020-14884-y

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