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A(2B) adenosine receptor inhibition by the dihydropyridine calcium channel blocker nifedipine involves colonic fluid secretion

The adenosine A(2B) receptor is a critical protein in intestinal water secretion. In the present study, we screened compound libraries to identify inhibitors of the A(2B) receptor and evaluated their effect on adenosine-induced intestinal fluid secretion. The screening identified the dihydropyridine...

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Detalles Bibliográficos
Autores principales: Asano, Teita, Noda, Yuto, Tanaka, Ken-Ichiro, Yamakawa, Naoki, Wada, Mitsuhito, Mashimo, Tadaaki, Fukunishi, Yoshifumi, Mizushima, Tohru, Takenaga, Mitsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044278/
https://www.ncbi.nlm.nih.gov/pubmed/32103051
http://dx.doi.org/10.1038/s41598-020-60147-7