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A(2B) adenosine receptor inhibition by the dihydropyridine calcium channel blocker nifedipine involves colonic fluid secretion
The adenosine A(2B) receptor is a critical protein in intestinal water secretion. In the present study, we screened compound libraries to identify inhibitors of the A(2B) receptor and evaluated their effect on adenosine-induced intestinal fluid secretion. The screening identified the dihydropyridine...
Autores principales: | Asano, Teita, Noda, Yuto, Tanaka, Ken-Ichiro, Yamakawa, Naoki, Wada, Mitsuhito, Mashimo, Tadaaki, Fukunishi, Yoshifumi, Mizushima, Tohru, Takenaga, Mitsuko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044278/ https://www.ncbi.nlm.nih.gov/pubmed/32103051 http://dx.doi.org/10.1038/s41598-020-60147-7 |
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