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Intestinal ex vivo organoid culture reveals altered programmed crypt stem cells in patients with celiac disease

The ex vivo generation of gastrointestinal organoids from crypt stem cells opens up the possibility of new research approaches investigating gastrointestinal diseases. We used this technology to study differences between healthy controls and patients with celiac disease (CD). We noticed distinct dis...

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Detalles Bibliográficos
Autores principales: Dieterich, Walburga, Neurath, Markus F., Zopf, Yurdagül
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044285/
https://www.ncbi.nlm.nih.gov/pubmed/32103108
http://dx.doi.org/10.1038/s41598-020-60521-5